Electrophy is a program to analyse electrophysiological data for MS-Windows 2000 and up.
Electrophy accepts ASCII data, ISO-2 data and files in AxonInstruments formats for the PC (*.dat and *.abf until v1.83, PClamp, Fetch etc) and the MacIntosh (Axograph type 1 and 2). Consult this Molecular Devices page for the conversion of v2 (PClamp 10) to v1.83 (PClamp 9) file format.
Electrophy outputs a vector drawing ready for publication.
(contextual) Help is provided in HTML.
Browse the online manual.
In only minutes carry out baseline correction, leak and common signal subtraction, detect single channel openings, synaptic currents or spikes with high precision and make your publish-ready dwell time histograms,dot plots, post/peri stimulus time histograms (PSTH), spike interval histograms, EPSP size, rise or decay time histograms etc.
Rapid detection of synaptic currents using a user-defined template, stacked minis are recognised with high temporal resolution:
Simulation of synaptic currents, unitary patch-clamp currents, macroscopic currents and dwell time histograms.
Estimation of rate constants in a Markov chain model, using your experimental data (macroscopic currents and single-channel dwell time histograms).
Statistical tests for data in spreadsheet columns: linear correlation, chi-2 test, Student's t-test, Fisher's F-test, Tukey's q-test (one-way anova).
Carry out curve fitting using either build-in or user-defined functions.
Data other than AxoLab files (PClamp, Axograph) may be imported in (tab- or comma-delimited) ASCII format.
With the JRTalk extension Electrophy may be controlled by a program you have written in Visual Basic, Mediacy's IP+ script or C.
Electrophy is amply documented and help is provided in several ways: by key word search, by context and by menu item. The doc file includes a comprehensive step by step tutorial. Under Windows 10, the tutorial can be found by clicking "All applications" in the start menu. Then look for the Electrophy folder, which contains Electrophy.doc.
Many of the techniques and routines for data analysis used in Electrophy are discussed in
"Introduction to Electrophysiological Methods and Instrumentation" by F. Bretschneider and J.R. de Weille.
The second edition will be out november 1st.